Finally a reef safe marine ich treatment that works. I bought 4 bottles and treated at max dose of 3 scoops per 50 gallons, twice per day for 24 days. Raised the temperature to 82-84 degrees. Ich pretty much covered all the tangs. My tank has 25 tangs (including 1 gem, 1 blue powder, 1 brown powder, 3 achilles, 1 sail fin, 2 purple, 3 yellow, 5 blue hippo, 1 scopas, 3 sohal, 2 blonde naso, 1 naso, and 1 lieutenant tang), 19 clowns, 1 cleaner wrasse, and 1 cleaner goby. All 46 fish survived and all corals and inverts doing fine. I only lost a giant clam and two SPS but it's worth it to save all my fish.. You must go max dose and run to whole 20 days. The ich battled the Medic all the way to the last day so I added 4 extra days to make sure. Great product!!!